Longevity & Bio Optimisation
JADE+ ONE
Protocol 011 · Longevity & Bio Optimisation
The levers of ageing, daily.
For metabolic resilience and long-term function — not managing a condition, but optimising the variables that determine how well you function at every age. AETHERA ONE is the daily foundation.
The biology
Ageing isn't one process — but a handful of levers move most of it. NAD+ powers DNA repair and sirtuin activity and falls with age. Mitochondria generate the energy every tissue runs on. Muscle and brain need creatine. Chronic low-grade inflammation accelerates everything. ONE addresses these foundational systems together, daily, rather than chasing a single anti-ageing claim.
What this protocol targets
NAD+ & sirtuins
NMN as a direct NAD+ precursor, with trans-resveratrol to support sirtuin-mediated repair.
Mitochondrial energy
Ubiquinol — the active, body-ready form of CoQ10 — for cellular energy production.
Muscle & brain
Creatine for strength, power and increasingly-evidenced cognitive benefit at every age.
Inflammation & defence
High-EPA omega-3 and NAC/glutathione for inflammatory resolution and antioxidant capacity.
Who it's for
- People optimising long-term function rather than managing an acute condition
- Anyone focused on healthy ageing, energy and cognitive longevity
- High performers who want a clean, evidence-led daily foundation
The formulas
The full ONE protocol — below. Find your protocol →