Perimenopause & Menopause
JADE+ PRIME
Protocol 002 · Perimenopause & Menopause
The transition, met with evidence.
Perimenopause isn't a single symptom — it's sleep, metabolism, mood, body composition and cognition shifting together as oestrogen declines. AETHERA PRIME supports each pathway with the compounds that actually have clinical evidence in women, not a generic "menopause blend."
The biology
As oestrogen and progesterone decline, sleep fragments, cortisol climbs, lean mass and bone erode faster, and inflammatory load rises. These aren't separate complaints to treat one at a time — they're downstream of one hormonal shift. PRIME works across the whole cascade rather than chasing a single symptom.
What this protocol targets
Lean mass & bone
Creatine, collagen and clinical-dose protein to protect the muscle and bone that decline fastest in this window.
Sleep & cortisol
Magnesium glycinate, glycine and KSM-66 ashwagandha for the broken sleep and raised stress response.
Inflammation
High-EPA omega-3 to support mood, joints and cardiovascular health as oestrogen's protection fades.
Energy & mood
Adaptogenic and nervous-system support for the fatigue, volatility and brain fog of the transition.
Who it's for
- Women in their late 30s to 50s noticing sleep, mood, cycle or body-composition changes
- Anyone dismissed by standard care who wants evidence over a generic women's blend
- Those protecting muscle, bone and cognition through the hormonal shift
The formulas
The full PRIME protocol — below. New here? Find your protocol →
